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Fibroblast Growth Factor

This from a doctor with an autistic child points to an area of which I know nothing. You may want to investigate it with your doctor or contact Dr. Aguilar for further information. “Out of pure desperation in January, I made an appointment with Dr. Luis Aguilar for FGF2 (Fibroblast Growth Factor 2) for Mike. He gave an address to the 1997 DAN! conference in which he presented his results using FGF2 in autism. They were very impressive in younger children (ages 3 to 5). Mike got his first FGF2 injection on April 19th; he gets an injection every 10 days. His response has been remarkable with major improvement in EEG with VEP’s that Dr. Aguilar uses for assessment, and with big improvements in language, especially expressive (he was nonverbal).”

FGF-2 is a growth factor with receptors present on cells in specific areas of the brain damaged in autism, such as the hippocampus, amygdala, hypothalamus, mesencephalic trigeminal nucleus, and cerebellum. FGF-2 normally acts to stimulate neuronal cell growth from stem cells (the “progenitor” cells that can turn into the various types of cells present in a normal brain) and blood vessel regeneration (necessary for carrying nutrients into the brain). FGF-2 also stimulates the bone marrow, which produces immune stem cells, and the thymus, which contributes to immune cell development. This growth factor is also present in the intestines to regulate healing and repair. Homeopathic dilutions of FGF-2 are theorized to help autism by stimulating brain, stem-cell regeneration, blood-vessel growth, bone-marrow functioning, and intestinal healing without the side effects and expense of injectable FGF-2, such as increased inflammation and disordered astrocyte (brain immune cell) turnover. “The greatest strength of growth factors and CSE-homeopathic growth factors of Biomed Comm ( is their ability to bring ‘abnormal’ cells working out of control back into normal homeostasis”—Barbara Brewitt, Ph.D., Chief Scientific Officer.

Scientists at the Michigan School of Medicine have found that rats that had experienced a stoke or had epileptic seizures responded to these injuries by sending primitive neuronal cells into the damaged areas, attempting to form new neurons. In culture dishes, these precursor cells have been shown to normally generate only glial cells (housekeeping cells that provide support and nutrition to nerve cells). What these scientists discovered is that when these cells are exposed to FGF-2, they seemed to have the ability to generate neurons!

In tests, aloe vera extract stimulated fibroblasts that grow and repair tissue (Sugars That Heal). Mannose (Aloe Vera) has been shown to stimulate the production of mucopolysaccharides (GAGs) in fibroblast cells. This may contribute to the enhanced, wound healing associated with aloe vera. [Chithra P, Sajithlal GB, Chandrakasan G J. Influence of aloe vera on the glycosaminoglycans in the matrix of healing dermal wounds in rats. Ethnopharmacol 1998 Jan;59(3):179-86]. Recent research showed a dose-related, positive effect of blueberries, green-tea catechins, carnosine, and vitamin D3 on the proliferation of human bone marrow. Combinations of these nutrients stimulated bone marrow proliferation by as much as 83% compared to only 43% in the control group which received a growth factor called “granulocyte colony-stimulating factor”. Additionally, supplementing with the omega-3 fatty acid, DHA favorably influences adult stem-cell repair. Mannatech’s Ambrotose Complex (includes an aloe vera component and other mannose sources) also has been observed to increase stem-cell production by the bone marrow. These nutrients, coupled with support for the thymus (a multivitamin/mineral plus a thymus glandular extract), should provide many vital improvements at a fraction of the cost of FGF-2 injections that are available only in Mexico.

A 24-year study of 11,384 people by James E. Ensrom of The University of Southern California found that those taking supplements cut their death rate in half! Deaths from cancer and heart disease were less than 10% of those who did not take a supplement. A Harvard study (Annuls of Internal Medicine 10/1/08) of 89,300 women found that daily multivitamins reduced the risk of colon cancer by as much as 75%! A British study (Br j Psychiatry 2002;181:22-8) of adult prisoners found that those given a multivitamin/mineral with essential fatty acids had 26.3% less violent acts and antisocial behavior!

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